Harry Winks has been ruled out of action for for the remainder of the season, after sustaining a ligament injury against Burnley.
The English midfielder was stretchered off in the 2-0 win over Burnley after colliding with Stephen Ward.
A statement from the club said: “Harry Winks will continue to be monitored by our medical team during his recovery and will be unavailable for the remainder of the season.”
Pochettino believes the midfielder can grow into one of the best in England.
“He was playing well and I’m sure in time would have been considered by Gareth Southgate,” Pochettino said.
“He is a very good prospect, a player who is dynamic and aggressive. He needs time to be consistent but in time he can be one of the best midfielders for England.”